Challenges in Comparing Crushing Force Test Results
Comparing test results isn’t always straightforward. Especially conventional methods like crushing force measurement can have some pitfalls.
The US Pharmacopeia outlines two measurement principles, constant speed and constant force increase. But is this really enough to algin test results?
After all, the hardness of tablets is one of the most important quality parameters in developing and manufacturing tablets.
Aspects potentially leading to varied outcomes include:
👉 Measuring mode (constant speed vs. constant force increase)
👉 Test speed (0.05 mm/sec – 3.5 mm/sec)
👉 Different units for measured force (Newton [N], Kilopond [kp], Strong Cobb [SC])
👉 Constant positioning of the tablet in the device (depending on tablet shape)
👉 Device type
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