Calculating Compaction Pressure: Key to Effective Tablet Formulation.
Normalizing the compaction force can be done by calculating the compaction pressure.
This is important if you, for example, develop a new formulation and process with another tablet size or shape.
Using the pressure, you can easily calculate thetarget forces to be achieved by changing to the target shape.
Also, if you want to compare the results of different shapes, normalization is necessary.
For flat tablets, it is simple to calculate the pressure from the force and the surface area.
If you want to calculate the pressure for non-flat tablets, this is done byusing the cross-sectional area. In fact, you ignore the radius of curvature.